Pro-enkephalin in plasma of surgical icu-patients with sepsis - a pilot study

نویسندگان

  • S Doemming
  • T-P Simon
  • A Humbs
  • L Martin
  • C Bruells
  • O Hartmann
  • J Struck
  • A Bergmann
  • G Marx
  • T Schuerholz
چکیده

Introduction Enkephalins are opioid peptides and enkephalin and its precursor pro-enkephalin (pro-ENK) are found to be widely distributed in organ tissues including the kidney [1]. Pro-ENK is a predictor for acute kidney injury (AKI) in patients after cardiac surgery and can detect severity of AKI in patients admitted to the emergency department with sepsis [2,3]. In surgical ICU-patients with sepsis, information on the suitability of pro-ENK to determine kidney function is lacking.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2015